BENZNIDAZOLE AND AMIODARONE COMBINED TREATMENT ATTENUATES CYTOSKELETAL DAMAGE IN TRYPANOSOMA CRUZI-INFECTED CARDIAC CELLS

Benznidazole and amiodarone combined treatment attenuates cytoskeletal damage in Trypanosoma cruzi-infected cardiac cells

Chagas disease (CD), a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi, is an important public health problem mainly in Latin America, leading to approximately 12,000 annual deaths.Current etiological treatment for CD is limited to two nitro compounds, benznidazole (Bz) and nifurtimox (Nif), both presenting relevant li

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An Overview of the Pathogenesis, Transmission, Diagnosis, and Management of Endemic Human Coronaviruses: A Reflection on the Past and Present Episodes and Possible Future Outbreaks

The outbreak of the 2019 coronavirus pandemic caught the world by surprise in late 2019 and has held it hostage for months with Snack Bowls an increasing number of infections and deaths.Although coronavirus was first discovered in the 1960s and was known to cause respiratory infection in humans, no information was available about the epidemic patte

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Stoichiometrically Governed Curcumin Solid Dispersion and Its Cytotoxic Evaluation on Colorectal Adenocarcinoma Cells

Jamal Moideen Muthu Mohamed,1 Ali Alqahtani,2 Fazil Ahmad,3 V Krishnaraju,2 K Kalpana4 1Department of Pharmaceutical Technology, BIT Campus, Anna University, Tiruchirappalli, Tamil Nadu 620024, India; 2Department of Pharmacology, College of Pharmacy, King Khalid University, Guraiger, Abha 62529, Saudi Arabia; 3Department of Anesthesia Technology, C

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